Figure 4.

Plots of (w_{ces Lp} − w_{ces L})/w_{ces Lp} versus (w_{dis Lp} − w_{dis L})/w_{dis Lp} showing how changes in the lipid composition of a dataset will impact each control function relative to the pivot species. Lipid species that fall on the line of equality (or close to it) have roughly equal effects on the magnitude of p_ces and p_dis. Panel (a) shows the lipids classified by headgroup identity. Panel (b) shows the lipids classified by the total number of unsaturations in both hydrocarbon chains. Panel (c) shows the lipids classified into three groups (Groups 1a, 1b and 2) as discussed in the text. Panel (d) shows the relative changes in p_ces and p_dis about the cell cycle of the HeLa cell; p_ces data were normalized to the p_ces value at 3 h and p_dis data were normalized to the p_dis value at 3 h. G1, S, G2 and M are the Gap 1, Synthesis, Gap 2 and Mitosis phases respectively and x-axis is the number of hours after the release of cells from synchronization agent [47]. Increases in p_ces over p_dis during G2/M are driven by compositional increases in polyunsaturated lipids.