Table 1. Characteristics and genotypes of HCV in patients with HIV/HCV co-infectiona.
| South | Central | Northwest | Total | P value | |
|---|---|---|---|---|---|
| N = 317 | N = 60 | N = 37 | N = 414 | ||
| Age | 36±6 | 42±8 | 34±7 | 37±7 | <0.001 |
| Sex (Male%) | 240 (75.7) | 31 (51.7) | 31 (83.8) | 302 (72.9) | <0.001 |
| HCV viral load (log10IU/mL) | 5.54±1.07 | 6.07±1.09 | 6.15±1.01 | 5.67±1.09 | <0.001 |
| ALT (U/L) | 66±47 | 59±39 | 74±47 | 66±46 | 0.343 |
| AST (U/L) | 63±45 | 52±33 | 53±23 | 60±42 | 0.868 |
| Risk behaviors (%) | <0.001 | ||||
| IDU | 254 (80.1) | 31 (51.7) | 14 (37.8) | 299 (72.2) | |
| Sex | 48 (15.1) | 3 (5.0) | 2 (5.4) | 53 (12.8) | |
| Blood transfusion | 5 (1.6) | 17 (28.3) | 1 (2.7) | 23 (5.6) | |
| Unknown | 10 (3.2) | 9 (15.0) | 20 (54.1) | 39 (9.4) | |
| Genotype | <0.001 | ||||
| Genotype 1 (%) | 64 (20.2) | 37 (61.7) | 17 (45.9) | 118 (28.5) | |
| 1a | 22 (6.9) | 0 (0) | 1 (2.7) | 23 (5.6) | |
| 1b | 42 (13.2) | 37 (61.7) | 16 (43.2) | 95 (22.9) | |
| Genotype 2 (%) | 2 (0.6) | 18 (30.0) | 1 (2.7) | 21 (5.1) | |
| 2a | 2 (0.6) | 18 (30.0) | 1 (2.7) | 21 (5.1) | |
| Genotype 3 (%) | 132 (41.6) | 2 (3.3) | 16 (43.2) | 150 (36.2) | |
| 3a | 58 (18.3) | 2 (3.3) | 12 (32.4) | 72 (17.4) | |
| 3b | 74 (23.3) | 0 (0) | 4 (10.8) | 78 (18.8) | |
| Genotype 5 (%) | 0 (0) | 0 (0) | 1 (2.7) | 1 (0.2) | |
| 5a | 0 (0) | 0 (0) | 1 (2.7) | 1 (0.2) | |
| Genotype 6 (%) | 119 (37.6) | 3 (5.1) | 2 (5.4) | 124 (30.0) | |
| 6a | 98 (30.9) | 1 (1.7) | 2 (5.4) | 101 (24.4) | |
| 6n | 17 (5.4) | 1 (1.7) | 0 (0) | 18 (4.3) | |
| 6u | 0 (0) | 1 (1.7) | 0 (0) | 1 (0.2) | |
| 6v | 4 (1.3) | 0 (0) | 0 (0) | 4 (1.0) |
IDU, injection drug users; ALT, alanine aminotransaferase; AST, aspirate aminotransferase
aData are presented as a mean±SD or number (%) of patients.