Table 2. Genotype frequencies of microRNA gene polymorphisms in controls and ischemic stroke patients.

SNP	Genotype	Control (n = 400)	Stroke (n = 523)	AOR (95% CI)	P	FDR-P
miR-130bT>C rs373001	TT	228 (57.0)	290 (55.4)	1.000 (reference)
	TC	144 (36.0)	192 (36.7)	1.021 (0.764–1.365)	0.887	0.887
	CC	28 (7.0)	41 (7.8)	1.168 (0.686–1.989)	0.568	0.852
	Dominant (TT vs TC+CC)			1.047 (0.795–1.378)	0.745	0.745
	Recessive (TT+TC vs CC)			1.173 (0.698–1.972)	0.548	0.548
miR-200bT>C rs7549819	TT	174 (43.5)	238 (45.5)	1.000 (reference)
	TC	177 (44.3)	236 (45.1)	0.976 (0.731–1.302)	0.867	0.887
	CC	49 (12.3)	49 (9.4)	0.748 (0.470–1.191)	0.221	0.663
	Dominant (TT vs TC+CC)			0.929 (0.706–1.222)	0.599	0.745
	Recessive (TT+TC vs CC)			0.762 (0.491–1.182)	0.224	0.548
miR-495A>C rs2281611	AA	102 (25.5)	123 (23.5)	1.000 (reference)
	AC	196 (49.0)	280 (53.5)	1.116 (0.798–1.560)	0.523	0.887
	CC	102 (25.5)	120 (22.9)	0.969 (0.654–1.435)	0.875	0.875
	Dominant (AA vs AC+CC)			1.065 (0.776–1.462)	0.697	0.745
	Recessive (AA+AC vs CC)			0.895 (0.651–1.231)	0.496	0.548

Data are derived by multivariate logistic regression adjusted for age, sex, hypertension, diabetes mellitus, hyperlipidemia, and current smoking. AOR = adjusted odds ratio, CI = confidence interval, FDR = false discovered rate, SNP = single nucleotide polymorphism.