Table 3. Annotated down regulated salivary proteins in An. culicifacies upon blood feeding.

Match ID/ Fold decrease	Accession	Protein	Organism, % sequence coverage	Peptide matches	Function/ Signal peptide if any
0/0.17	B0WIV8	Putative uncharacterized protein	Culex quinquefasciatus, 22%	7	Caspase recruitment domain
	A0A084VT63	Isocitrate dehydrogenase	An. sinensis, 29%	12	Oxidation reduction
3/0.38	A0A023EUU0	Putative juvenile hormone epoxide hydrolase ii	Ae. albopictus, 22%	8	Physiological change/ Signal P: 1–19
	Q6TRY1	Putative salivary OBP 2	Culex quinquefasciatus, 27%	2	Signal P: 1–20
	A0A023EVV5	Putative pftaire-interacting factor 1a	Ae. albopictus, 23%	14	Unknown
12/0.37	B0W7K8	Chemosensory protein 1	Culex quinquefasciatus, 71%	8	OBP 10
14/0.42	A0A023EFB5	Putative 11 kDa salivary protein	Ae. albopictus, 60%	4	Magnesium transport/ Signal P: 1–19
27/0.34	W5JJH0	Sphingosine phosphate lyase	An. darling, 13%	8	Apoptosis regulation
	O17491	Iron regulatory protein	An. gambiae, 17%	5	Iron homeostasis