Table 3. Mean tumor perfusion parameters for the whole patient cohort before, during, and after RT.
Parameter (mean value) | Baseline before RT (n = 15) | During RT | 6 wk after RT (n = 12) | ||
---|---|---|---|---|---|
| |||||
Week 2 (n = 15) | Week 4 (n = 14) | Week 6 (n = 11) | |||
BF (mL/100 g/min) | 16.9 (6.6) | 25.7 (16.7) | 46.0 (25.9) | 36.0 (23.0) | 32.7 (12.7) |
BV (mL/100 g) | 1.6 (0.68) | 2.0 (0.70) | 2.5 (0.86) | 2.8 (1.5) | 3.6 (1.6) |
MTT (s) | 8.3 (3.5) | 9.4 (4.1) | 6.6 (4.1) | 7.9 (3.7) | 8.3 (2.7) |
CP (mL/100 g/min) | 6.0 (4.8) | 6.6 (7.3) | 8.5 (5.9) | 13.7 (12.3) | 13.2 (15.5) |
Abbreviations: RT = radiotherapy; BF = blood flow; BV = blood volume; MTT = mean transit time; CP = capillary permeability. Data are presented as mean (SD). Capillary permeability was not recorded for 2 patients at Week 2 (n = 13) and 1 patient at Week 6 (n = 10).