Table 5. Computed tomography perfusion parameters (percentage change from baseline) correlated to dysphagia severity at 3- and 6-month follow-up.
Parameter | No. of scans | Dysphagia Grade 0–2 | Dysphagia Grade 3 | p | ||||
---|---|---|---|---|---|---|---|---|
|
|
|||||||
n | Mean | SE | n | Mean | SE | |||
Blood flow | ||||||||
3-mo follow-up | ||||||||
Week 2 | 15 | 10 | 43.0 | 38.8 | 5 | 130.5 | 54.8 | 0.083 |
Week 4 | 14 | 9 | 195.1 | 70.6 | 5 | 275.8 | 94.8 | 0.366 |
Week 6 | 11 | 9 | 91.2 | 39.5 | 2 | 287.2 | 83.7 | 0.141 |
6 wk after RT | 12 | 8 | 82.2 | 58.5 | 4 | 240.4 | 82.7 | 0.132 |
6-mo follow-up | ||||||||
Week 2 | 15 | 9 | 12.3 | 34.6 | 6 | 161.9 | 42.4 | 0.007 |
Week 4 | 14 | 8 | 205.4 | 75.9 | 6 | 248.6 | 87.7 | 0.417 |
Week 6 | 11 | 8 | 84.5 | 43.5 | 3 | 239.9 | 71.0 | 0.121 |
6 wk after RT | 12 | 7 | 88.6 | 65.9 | 5 | 199.9 | 78.0 | 0.265 |
Blood volume | ||||||||
3-mo follow-up | ||||||||
Week 2 | 15 | 10 | 12.0 | 27.2 | 5 | 107.7 | 38.5 | 0.044 |
Week 4 | 14 | 9 | 58.3 | 45.4 | 5 | 162.8 | 60.9 | 0.189 |
Week 6 | 11 | 9 | 80.9 | 91.3 | 2 | 552.6 | 193.8 | 0.217 |
6 wk after RT | 12 | 8 | 105.9 | 98.8 | 4 | 414.3 | 139.7 | 0.096 |
6-mo follow-up | ||||||||
Week 2 | 15 | 9 | 8.7 | 29.1 | 6 | 96.6 | 35.6 | 0.039 |
Week 4 | 14 | 8 | 54.6 | 48.5 | 6 | 150.4 | 56.0 | 0.163 |
Week 6 | 11 | 8 | 80.0 | 106.7 | 3 | 397.8 | 174.2 | 0.280 |
6 wk after RT | 12 | 7 | 82.4 | 104.6 | 5 | 385.6 | 123.8 | 0.040 |
Capillary permeability | ||||||||
3-mo follow-up | ||||||||
Week 2 | 13 | 9 | 31.6 | 33.8 | 4 | -48.3 | 50.6 | 0.090 |
Week 4 | 14 | 9 | 320.3 | 154.8 | 5 | 205.7 | 207.7 | 0.299 |
Week 6 | 10 | 8 | 589.7 | 482.3 | 2 | 1907.4 | 964.5 | 0.357 |
6 wk after RT | 12 | 8 | 603.8 | 244.0 | 4 | 243.3 | 345.1 | 0.640 |
6-mo follow-up | ||||||||
Week 2 | 13 | 8 | 43.1 | 34.3 | 5 | -50.7 | 43.4 | 0.062 |
Week 4 | 14 | 8 | 372.6 | 160.3 | 6 | 155.2 | 185.2 | 0.848 |
Week 6 | 10 | 7 | 652.4 | 546.4 | 3 | 1322.0 | 834.7 | 0.371 |
6 wk after RT | 12 | 7 | 694.0 | 249.7 | 5 | 189.1 | 295.5 | 0.350 |
Mean transition time | ||||||||
3-mo follow-up | ||||||||
Week 2 | 15 | 10 | 29.0 | 20.6 | 5 | 25.0 | 29.2 | 0.944 |
Week 4 | 14 | 9 | 6.9 | 28.8 | 5 | -13.3 | 38.7 | 0.802 |
Week 6 | 11 | 9 | 8.7 | 24.4 | 2 | 65.4 | 51.7 | 0.988 |
6 wk after RT | 12 | 8 | 20.9 | 29.4 | 4 | 68.9 | 41.5 | 0.297 |
6-mo follow-up | ||||||||
Week 2 | 15 | 9 | 38.4 | 21.3 | 6 | 11.6 | 26.0 | 0.447 |
Week 4 | 14 | 8 | 9.5 | 30.5 | 6 | -13.4 | 35.2 | 0.871 |
Week 6 | 11 | 8 | 15.5 | 27.2 | 3 | 28.4 | 44.3 | 0.524 |
6 wk after RT | 12 | 7 | 28.7 | 32.5 | 5 | 48.5 | 38.4 | 0.578 |
Abbreviation as in Table 3.