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Histologic findings in IOI mice after administration of doxycycline for 8 weeks and treatment with Etanercept during the last 2 weeks thereof. Neural cell adhesion molecule (NCAM) immunohistochemistry. The diameter of the subepithelial axon bundle was significantly thickened compared with Figure 4(D). Red staining indicates NCAM and blue staining is the nuclear marker, DAPI (250×). White broken line indicates the basement membrane. Scale bar = 25µm.
