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. 2016 Sep 7;11(9):e0162432. doi: 10.1371/journal.pone.0162432

Fig 4. Milk fatty acid composition and mRNA expression of fat-related genes were altered in response to high fat or low fat diet fed to wild type or Tph1 deficient dams.

Fig 4

Wild type or Tph1 deficient dams were either fed a high fat or low fat diet throughout pregnancy and lactation. Shown are the effects on (A) relative abundance of various fatty acids in milk from early lactation, (B) relative abundance of various fatty acids in milk on day 10 of lactation, (C) mammary gland mRNA expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, (D) mammary gland mRNA expression of insulin-like growth factor binding protein 5, (E) mammary gland mRNA expression of cholecystekinin. Values are means ± SEMs. Stars indicate statistical significance between groups (* = 0.05<P<0.01, ** = 0.01<P<0.001, *** = 0.001<P<0.0001, **** = P<0.0001). WT, wild type; Tph1-/-, Tph1 deficient; LFD, low fat diet; HFD, high fat diet.