Table 1.

The four living species datasets description.

Speciesa	DS Idb	GEO_IDc	Ref.d	Tissuee	#Samplesf	#Genesg	#Groups (classes)h
Fly	F_dataset1	GSE10169	[15]	Whole body	12	12,522	4
	F_dataset2	GSE32912	[16]	S2 cell	21	12,522	11
Worm	W_dataset1	GSE9896	[17]	Whole body	10	16,812	2
	W_dataset2	GSE9897	[18]	Whole body	10	16,812	6
	W_dataset3	GSE46051	[19]	Whole body	22	28,355	8
Human	H_dataset1	GSE1462	[20]	Skeletal muscle	15	12,027	4
	H_dataset2	GSE8648	[21]	Fibroblast	22	1,190	2
	H_dataset3	GSE10956	[22]	Fibroblast	22	13,031	2
	H_dataset4	GSE14882	[23]	Peripheral blood	16	12,027	2
	H_dataset5	GSE24945i	[24]	Fibroblast	12	19,617	4
	H_dataset6	GSE26322	[25]	Fibroblast	12	19,063	2
	H_dataset7	GSE27041	[26]	Fibroblast	20	18,895	4
	H_dataset8	GSE27545	[27]	Cybrid	17	19,600	6
	H_dataset9	GSE28206	[28]	Skeletal muscle	7	19,600	2
	H_dataset10	GSE33769	[29]	Fibroblast	15	18,895	2
	H_dataset11	GSE33940	[30]	Fibroblast	20	19,714	3
	H_dataset12	GSE35642	[31]	SK-N-MC cell	18	12,027	6
	H_dataset13	GSE42986	[32]	Muscle/FCL	40	20,708	4
Mouse	M_dataset1	GSE4330	[33]	Myoblast (C2C12)	21	14,706	7
	M_dataset2	GSE4866	[34]	Cochlea	10	17,480	2
	M_dataset3	GSE5332	[35]	MEF	13	17,480	4
	M_dataset4	GSE5786	[36]	Striata	6	20,628	2
	M_dataset5	GSE6210	[37]	Liver/Muscle	12	17,480	4
	M_dataset6	GSE10904	[38]	Liver	6	17,480	2
	M_dataset7	GSE13034	[39]	MEF	14	12,279	4
	M_dataset8	GSE18677i	[40]	Liver	11	17,480	8
	M_dataset9	GSE27309	[41]	Brown adipose	20	20,299	2
	M_dataset10	GSE27954	[42]	Liver	12	21,154	4
	M_dataset11	GSE30552	[43]	Liver	26	17,480	4
	M_dataset12	GSE34773	[44]	Skeletal muscle	26	17,480	4

^aThe dataset species.

^bDS Id is the dataset id number that is used in this study.

^cThe GEO_ID in the NCBI database.

^dThe dataset reference.

^eThe tissue that the sample comes from.

^fThe number of samples in the dataset.

^gThe number of genes in the dataset.

^hThe number of sample groups in the dataset.

ⁱToo many missing values in this dataset.