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. 2016 May 10;5(5):e319. doi: 10.1038/mtna.2016.31

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Copyright © 2016 Official journal of the American Society of Gene & Cell Therapy

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Percent of dose eliminated in excreta and found in tissue. (a) Mass percentages of cumulative radioactivity and total dose eliminated in Sprague Dawley rats following single s.c. administration of 4.3 mg/kg of ³H-ION 681257 labeled on the THA Linker at 114.4 µCi/kg (n = 2 rats, M). Values are listed as the percentage of normalized dose excreted in the urine, feces, and combined. (b) Percent of dose in major and minor tissues at 24 and 168 hours.