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Representative HPLC radiochromatograms of (a) dosing solution, (b) rat urine, (c) rat bile, and (d) rat feces. Conditions of the mobile phase evaluated include (black trace) 5 mmol/l ammonium acetate pH 8.0 and (blue trace) 0.1% aqueous formic acid pH 2.7. All samples were diluted to 100,000 DPM per 20 µl injection. DPM, disintegrations per minute; M#, identified metabolite listed in Table 1; P, parent; S, short-mer; U, unidentified.
