Table 2.

Clinical manifestation of thyrotoxicosis

	Symptoms	Signs
Constitutional	Weight loss despite increased appetite; heat-related symptoms (heat intolerance, sweating, and polydipsia)	Weight loss
Neuromuscular	Tremor; nervousness; anxiety; fatigue; weakness; disturbed sleep; poor concentration	Tremor of the extremities; hyperactivity; hyper-reflexia; pelvic and girdle muscle weakness
Cardiovascular	Palpitations	Tachycardia; systolic hypertension; irregular heartbeat (atrial fibrillation)
Pulmonary	Dyspnoea, shortness of breath	Tachypnoea
Gastrointestinal	Hyperdefecation; nausea, vomiting	Abdominal tenderness
Skin	Increased perspiration	Warm and moist skin
Reproductive	..	Menstrual disturbances
Ocular (Graves’ disease)	Diplopia; sense of irritation in the eyes; eyelid swelling; retro-orbital pain or discomfort	Proptosis; eyelid retraction and lag; periorbital oedema; conjunctival injection and chemosis; ophthalmoplegia