Table 6.
Demographic and Clinical Characteristics by Symptom Clusters Phenotype
| Demographic and Clinical Characteristics by Phenotype of Impaired Limb Mobility | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Impaired Limb Mobility Symptoms at 4-8 Weeks Post-Surgery | Total | Impaired Limb mobility Symptoms at 12 Months Post-Surgery | |||||||||||
| <2 Symptoms | 2+ Symptoms | <2 Symptoms |
2+ Symptoms |
||||||||||
| n = 57 | n = 79 | N= 136 | n = 61 | n = 75 | |||||||||
| Mean | SD | Mean | SD | p | Mean | SD | Mean | SD | Mean | SD | p | ||
| Age | 52.7 | 10.31 | 51.8 | 11.7 | 0.640a | 52.1 | 11.1 | 53.6 | 10.5 | 50.9 | 11.5 | 0.695a | |
| Weight (pounds) | 162.1 | 34.8 | 157.5 | 36.3 | 0.459a | 159.4 | 35.6 | 158.9 | 38.9 | 159.8 | 33.0 | 0.881a | |
| BMI | 28.7 | 6.2 | 27.0 | 6.3 | 0.132a | 27.7 | 6.3 | 27.4 | 6.4 | 28.0 | 6.3 | 0.563a | |
| n | % | n | % | p | n | % | n | % | n | % | p | ||
| Education | 0.182b | 0.030b | |||||||||||
| Associates degree or less | 22 | 38.6 | 23 | 29.1 | 45 | 33.1 | 14 | 23.0 | 31 | 41.3 | |||
| Bachelor’s degree | 27 | 47.4 | 35 | 44.3 | 62 | 45.6 | 29 | 47.5 | 33 | 44.0 | |||
| Graduate degree | 8 | 14.0 | 21 | 26.6 | 29 | 21.3 | 18 | 29.5 | 11 | 14.7 | |||
| Marital status | 0.864b | 0.834b | |||||||||||
| Married/partnered | 32 | 56.1 | 48 | 60.8 | 80 | 58.8 | 36 | 59.0 | 44 | 58.7 | |||
| Divorced/Widowed | 9 | 15.8 | 11 | 13.9 | 20 | 14.7 | 10 | 16.4 | 10 | 13.3 | |||
| Single, never partnered | 16 | 28.1 | 20 | 25.3 | 36 | 26.5 | 15 | 24.6 | 21 | 28.0 | |||
| Ethnicity | 0.960b | 0.682c | |||||||||||
| Black/African American | 11 | 19.3 | 16 | 20.3 | 27 | 19.9 | 12 | 19.7 | 15 | 20.0 | |||
| White Non-Hispanic | 36 | 63.2 | 46 | 58.2 | 82 | 60.3 | 36 | 59.0 | 46 | 61.3 | |||
| Asian | 5 | 8.8 | 8 | 10.1 | 13 | 9.6 | 5 | 8.2 | 8 | 10.7 | |||
| Hispanic/Latino | 4 | 7.0 | 8 | 10.1 | 12 | 8.8 | 6 | 9.8 | 9 | 8.0 | |||
| More than One Race | 1 | 1.8 | 1 | 1.3 | 2 | 1.5 | 2 | 3.3 | 0 | - | |||
| Employment | 0.447b | 0.168b | |||||||||||
| Unemployed | 8 | 14.0 | 15 | 19.0 | 23 | 16.9 | 7 | 11.5 | 16 | 21.3 | |||
| Employed | 49 | 86.0 | 64 | 81.0 | 113 | 83.1 | 54 | 88.5 | 59 | 78.7 | |||
| Surgery | <0.001b | 0.057b | |||||||||||
| Mastectomy | 3 | 5.3 | 12 | 15.2 | 15 | 11.0 | 3 | 4.9 | 12 | 16.0 | |||
| Lumpectomy | 40 | 70.2 | 26 | 32.9 | 66 | 48.5 | 35 | 57.4 | 31 | 41.3 | |||
| Mastectomy with immediate reconstruction |
14 | 24.6 | 41 | 51.9 | 55 | 40.4 | 23 | 37.7 | 32 | 42.7 | |||
| Nodes removed | Mean | SD | Mean | SD | 0.111d | Mean | SD | Mean | SD | Mean | SD | 0.269d | |
| 2.8 | 2.2 | 3.7 | 3.6 | 3.3 | 2.9 | 2.9 | 2.2 | 3.7 | 3.6 | ||||
| Nodes removed (Median) | Median 2 |
Median 3 |
Median 2 |
Median 2 |
Median 3 |
||||||||
| Chemotherapy | n = 28 | n= 47 | 0.006b | n= 75 | n = 25 | n = 50 | 0.004b | ||||||
| Neoadjuvant | 3 | 10.7 | 19 | 40.4 | 22 | 29.3 | 2 | 8.0 | 20 | 40.0 | |||
| Adjuvant | 25 | 89.3 | 28 | 59.6 | 53 | 70.7 | 23 | 92.0 | 30 | 60.0 | |||
| Radiation | 0.313b | 0.010b | |||||||||||
| No | 13 | 25.0 | 25 | 33.3 | 38 | 29.9 | 23 | 41.8 | 15 | 20.8 | |||
| Yes | 39 | 75.0 | 50 | 66.7 | 89 | 70.1 | 32 | 58.2 | 57 | 79.2 | |||
| Demographic and Clinical Characteristics by Phenotype of Fluid Accumulation | |||||||||||||
| Fluid Accumulation Symptoms at 4-8 Weeks Post-Surgery | Total | Fluid Accumulation Symptoms at 12 Months Post-Surgery | |||||||||||
| <2 Symptoms | 2+ Symptoms | <2 Symptoms | 2+ Symptoms | ||||||||||
| n=60 | n=76 | N =136 | n =76 | n = 60 | |||||||||
| Mean | SD | Mean | SD | p | Mean | SD | Mean | SD | Mean | SD | p | ||
| Age | 50.4 | 11.2 | 53.5 | 10.9 | 0.105a | 52.1 | 11.1 | 52.1 | 11.5 | 52.2 | 10.7 | 0.955a | |
| Weight (pounds) | 153.0 | 37.3 | 164.5 | 33.7 | 0.063a | 159.4 | 35.6 | 153.4 | 32.7 | 167.1 | 37.9 | 0.025a | |
| BMI | 26.4 | 6.2 | 28.8 | 6.2 | 0.032a | 27.7 | 6.3 | 26.5 | 5.9 | 29.2 | 6.4 | 0.010a | |
| n | % | n | % | p | n | % | n | % | n | % | p | ||
| Education | 0.730b | 0.168b | |||||||||||
| Associates degree or less | 20 | 33.3 | 25 | 32.9 | 45 | 33.1 | 21 | 27.6 | 24 | 40.0 | |||
| Bachelor’s degree | 29 | 48.3 | 33 | 43.4 | 62 | 45.6 | 35 | 46.1 | 27 | 45.0 | |||
| Graduate degree | 11 | 18.3 | 18 | 23.7 | 29 | 21.3 | 20 | 26.3 | 9 | 15.0 | |||
| Marital status | 0.124b | 0.8342b | |||||||||||
| Married/partnered | 40 | 66.7 | 40 | 52.6 | 80 | 58.8 | 46 | 60.5 | 34 | 56.7 | |||
| Divorced/Widowed | 5 | 8.3 | 15 | 19.7 | 20 | 14.7 | 10 | 13.2 | 10 | 16.7 | |||
| Single, never partnered | 15 | 25.0 | 21 | 27.6 | 36 | 26.5 | 20 | 26.3 | 16 | 26.7 | |||
| Ethnicity | 0.966c | 0.863c | |||||||||||
| Black/African American | 11 | 18.3 | 16 | 21.1 | 27 | 19.9 | 13 | 17.1 | 14 | 23.3 | |||
| White Non-Hispanic | 38 | 63.3 | 44 | 57.9 | 82 | 60.3 | 48 | 63.2 | 34 | 56.7 | |||
| Asian | 5 | 8.3 | 8 | 10.5 | 13 | 9.6 | 8 | 10.5 | 5 | 8.3 | |||
| Hispanic/Latino | 5 | 8.3 | 7 | 9.2 | 12 | 8.8 | 6 | 7.9 | 9 | 10.0 | |||
| More than One Race | 1 | 1.7 | 1 | 1.3 | 2 | 1.5 | 1 | 1.3 | 1 | 1.7 | |||
| Employment | 0.323b | 0.946b | |||||||||||
| Unemployed | 8 | 13.3 | 15 | 19.7 | 23 | 16.9 | 13 | 17.1 | 10 | 16.7 | |||
| Employed | 52 | 86.7 | 61 | 80.3 | 113 | 83.1 | 63 | 82.9 | 50 | 83.3 | |||
| Surgery | 0.818b | 0.129b | |||||||||||
| Mastectomy | 6 | 10.0 | 9 | 11.8 | 15 | 11.0 | 6 | 7.9 | 9 | 15.0 | |||
| Lumpectomy | 28 | 46.7 | 38 | 50.0 | 66 | 48.5 | 34 | 44.7 | 32 | 53.3 | |||
| Mastectomy with immediate reconstruction |
26 | 43.3 | 29 | 38.2 | 55 | 40.4 | 36 | 47.4 | 19 | 31.7 | |||
| Nodes removed | Mean 3 |
SD 2.1 |
Mean 3.5 |
SD 3.5 |
0.845d | Mean 3.3 |
SD 2.9 |
Mean 3.3 |
SD 3.2 |
Mean 3.3 |
SD 2.6 |
0.077d | |
| Nodes removed (Median) | Median 2 |
Median 2 |
Median 2 |
Median 2 |
Median 2 |
||||||||
| Chemotherapy | n = 35 | n = 40 | 0.006b | n= 75 | n = 37 | n = 38 | 0.051b | ||||||
| Neoadjuvant | 10 | 28.6 | 12 | 30.0 | 22 | 29.3 | 7 | 18.9 | 15 | 39.5 | |||
| Adjuvant | 25 | 71.4 | 28 | 70.0 | 53 | 70.7 | 30 | 81.1 | 23 | 60.5 | |||
| Radiation | 0.741b | 0.004b | |||||||||||
| No | 17 | 31.5 | 21 | 28.8 | 38 | 29.9 | 28 | 40.6 | 10 | 17.2 | |||
| Yes | 37 | 68.5 | 52 | 71.2 | 89 | 70.1 | 41 | 59.4 | 48 | 82.8 | |||
| Demographic and Clinical Characteristics by Phenotype of Discomfort | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Discomfort Symptoms at 4-8 Weeks Post-Surgery | Total | Discomfort Symptoms at 12 months Post-Surgery | ||||||||||||
| <2 Symptoms | 2+ Symptoms | <2 Symptoms | 2+ Symptoms | |||||||||||
| n = 19 | n = 117 | N= 136 | n = 84 | n = 52 | ||||||||||
| Mean | SD | Mean | SD | p | Mean | SD | Mena | SD | Mean | SD | p | |||
| Age | 51.7 | 12.7 | 52.2 | 10.9 | 0.865a | 52.1 | 11.1 | 51.9 | 11.5 | 52.6 | 10.6 | 0.696a | ||
| Weight (pounds) | 158.3 | 32.9 | 159.6 | 36.2 | 0.878a | 159.4 | 35.6 | 154.5 | 34.6 | 167.3 | 36.2 | 0.041a | ||
| BMI | 27.1 | 4.7 | 27.8 | 6.6 | 0.655a | 27.7 | 6.3 | 26.9 | 5.9 | 29.1 | 6.7 | 0.040a | ||
| n | % | n | % | p | n | % | n | % | n | % | p | |||
| Education | 0.480c | 0.039b | ||||||||||||
| Associates degree or less | 4 | 21.1 | 41 | 35.0 | 45 | 33.1 | 21 | 25.0 | 24 | 46.2 | ||||
| Bachelor’s degree | 10 | 52.6 | 52 | 44.4 | 62 | 45.6 | 43 | 51.2 | 19 | 36.5 | ||||
| Graduate degree | 5 | 26.3 | 24 | 20.5 | 29 | 21.3 | 20 | 23.8 | 9 | 17.3 | ||||
| Marital status | 0.474c | 0.949b | ||||||||||||
| Married/partnered | 9 | 47.4 | 71 | 60.7 | 80 | 58.8 | 49 | 58.3 | 31 | 59.6 | ||||
| Divorced/Widowed | 3 | 15.8 | 17 | 14.5 | 20 | 14.7 | 13 | 15.5 | 7 | 13.5 | ||||
| Single, never partnered | 7 | 36.8 | 29 | 24.8 | 36 | 26.5 | 22 | 26.2 | 14 | 26.9 | ||||
| Ethnicity | 0.982c | 0.507c | ||||||||||||
| Black/African American | 4 | 21.1 | 23 | 19.7 | 27 | 19.9 | 14 | 16.7 | 13 | 25.0 | ||||
| White Non-Hispanic | 11 | 57.9 | 71 | 60.7 | 82 | 60.3 | 54 | 64.3 | 28 | 53.8 | ||||
| Asian | 2 | 10.5 | 11 | 9.4 | 13 | 9.6 | 8 | 9.5 | 5 | 9.6 | ||||
| Hispanic/Latino | 2 | 10.5 | 10 | 8.5 | 12 | 8.8 | 6 | 7.1 | 6 | 11.5 | ||||
| More than One Race | 0 | - | 2 | 1.7 | 2 | 1.5 | 2 | 2.4 | 0 | - | ||||
| Employment | 0.741c | 0.923b | ||||||||||||
| Unemployed | 4 | 21.1 | 19 | 16.2 | 23 | 16.9 | 14 | 16.7 | 9 | 17.3 | ||||
| Employed | 15 | 78.9 | 98 | 83.8 | 113 | 83.1 | 70 | 83.3 | 43 | 82.7 | ||||
| Surgery | 0.292c | 0.035b | ||||||||||||
| Mastectomy | 0 | - | 15 | 12.8 | 15 | 11.0 | 7 | 8.3 | 8 | 15.4 | ||||
| Lumpectomy | 10 | 52.6 | 56 | 47.9 | 66 | 48.5 | 36 | 42.9 | 30 | 57.7 | ||||
| Mastectomy with immediate reconstruction |
9 | 47.4 | 46 | 39.3 | 55 | 40.4 | 41 | 48.8 | 14 | 26.9 | ||||
| Nodes removed | Mean 3.5 |
SD 5.2 |
Mean 3.2 |
SD 2.3 |
0.238d | 3.3 | 2.9 | 3.1 | 2.3 | 3.7 | 4.2 | 0.027d | ||
| Nodes removed (Median) | Median 2 |
Median 2 |
Median 2 |
Median 2 |
Median 2 |
|||||||||
| Chemotherapy | n =6 | n = 69 | 0.664c | n=75 | n = 40 | n=35 | 0.165b | |||||||
| Neoadjuvant | 1 | 16.7 | 21 | 30.4 | 22 | 29.3 | 9 | 22.5 | 13 | 37.1 | ||||
| Adjuvant | 5 | 83.3 | 48 | 69.6 | 53 | 70.7 | 31 | 77.5 | 22 | 62.9 | ||||
| Radiation | 0.370b | 0.001b | ||||||||||||
| No | 7 | 38.9 | 31 | 28.4 | 38 | 29.9 | 32 | 41.0 | 6 | 12.2 | ||||
| Yes | 11 | 61.1 | 78 | 71.6 | 89 | 70.1 | 46 | 59.0 | 43 | 87.8 | ||||
Independent groups t-test
Pearson Chi-square
Fisher’s exact test
Kruskal-Wallis test
SD Standard Deviation