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Experimental design highlighting patient selection criteria in discovery and expansion cohorts.
MSI-H: Microsatellite instability; MLH1: MutL homolog 1 protein; MLH3: MutL homolog 3 protein; MSH2: MutS protein homolog 2; MSH3: MutS protein homolog 3; MSH4: MutS protein homolog 4; MSH6: MutS protein homolog 6; PMS2: Mismatch repair endonuclease 2
