Table 2.

Mean changes from baseline to 24 months for study outcomes (in absolute values) with 95% confidence intervals (CI); by treatment group with between-treatment differences based on post-hoc estimates from the joint model.

	CYC			MMF			ΔMMF - ΔCYC
	N	change	95% CI	N	change	95% CI	Δ	95% CI
%-predicted FVC	51	2.88	1.19 to 4.58	53	2.19	0.53 to 3.84	−0.70	−3.1 to 1.7
%-predicted TLC	51	0.45	−1.43 to 2.32	53	1.24	−0.68 to 3.18	0.80	−2.0 to 3.6
%predicted DLCO	48	−2.14	−4.59 to 0.31	52	−0.40	−2.81 to 2.01	1.74	−1.6 to 5.1
%-predicted DL/VA	51	−3.43	−5.7 to −1.2	52	−2.46	−4.7 to −0.2	0.96	−2.2 to 4.1
TDI	39	2.16	1.14 to 3.18*	40	1.77	0.75 to 2.79	−0.39	−1.8 to 1.0
mRSS (including lcSSc & dcSSc)	53	−5.35	−6.9 to −3.8	53	−4.90	−6.4 to −3.4	0.45	−1.7 to 2.6
QLF-WL	47	1.13	−1.71 to 3.98	51	2.15	−0.72 to 5.03	1.02	−2.99 to 5.03
QLF-LM	47	−0.27	−1.43 to 1.69	51	0.12	−1.02 to 1.26	0.39	−1.27 to 2.05
QILD-WL	47	−1.84	−5.16 to 1.46	51	−0.95	−4.1 to 2.2	0.89	−3.58 to 5.36
QILD-LM	47	−2.78	−5.17 to −0.40	51	−2.51	−4.9 to −0.15	0.27	−3.09 to 3.67