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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2016 Apr 6;138(3):769–779. doi: 10.1016/j.jaci.2016.01.049

Figure 7. NSG-SGM3 BLT mice exhibit pronounced passive systemic anaphylaxis upon antigen challenge.

Figure 7

NSG-SGM3 BLT mice were sensitized by intravenous injection of chimeric human IgE anti-NP antibody and challenged 24 hours later by intravenous injection of NP-BSA in PBS. Systemic anaphylaxis was measured by (A) monitoring rectal body temperature and (B) by observable symptom scores, as described in Methods.

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