Table 3.

DNA methylation association with neuritic plaque pathology at target CpGs

CpG	Chr	Position (bp)	Brain (Est, SE, p)	T1 (Est, SE, p)	T2 (Est, SE, p)	Genes*
cg11724984	12	121890864	4.484, 1.611, 0.008	−4.476, 14.620, 0.761	−37.329, 16.193, 0.027	RNF34, KDM2B
cg23968456	10	73521631	8.923, 3.474, 0.014	0.292, 15.042, 0.985	3.861, 17.455, 0.826	CDH23, C10orf105, C10orf54
cg15821544	1	43473840	6.054, 2.591, 0.025	−18.283, 7.730, 0.023	0.629, 7.262, 0.931	SLC2A1, FLJ32224
cg16733298	16	19127132	4.533, 1.546, 0.006	5.073, 5.680, 0.378	1.841, 4.879, 0.708	COQ7, ITPRIPL2
cg22962123	7	27153605	2.433, 1.118, 0.036	12.066, 8.077, 0.144	−6.713, 4.742, 0.165	HOXA1, HOTAIRM1, HOXA2, AK291164, HOXA3, AK311383, BC035889, HOXA4, LOC100133311, HOXA5, HOXA6, DQ655986, HOXA7, HOXA9, HOXA10
cg13076843	17	74475294	2.664, 1.204, 0.033	−3.627, 6.847, 0.599	−7.978, 6.577, 0.233	UBE2O, AANAT, RHBDF2, AX747521, CYGB, PRCD
cg25594100	7	4786943	5.983, 1.679, 0.001	−14.313, 8.775, 0.111	−2.784, 9.799, 0.778	FOXK1, AP5Z1 (KIAA0415), RADIL
cg00621289	21	47855916	7.654, 2.446, 0.003	2.541, 3.762, 0.504	−9.643, 4.714, 0.048	PCNT, DIP2A
cg19803550	17	1637391	7.797, 2.310, 0.002	3.197, 9.073, 0.727	2.193, 12.778, 0.865	PRPF8, TLCD2, MIR22HG, AF070569, MIR22, WDR81, SERPINF2, SERPINF1, SMYD4
cg03169557	16	89598950	7.012, 2.428, 0.006	−5.847, 6.425, 0.369	−25.303, 18.51, 0.180	ANKRD11, SPG7, SNORD68, RPL13, CPNE7
cg05066959	8	41519308	2.357,1.360, 0.091	−4.726, 2.455, 0.062	0.109, 2.765, 0.969	AGPAT6, NKX6-3, JA429246, ANK1
cg05810363	17	74475270	3.502,1.744, 0.052	−11.120, 15.853, 0.487	−13.722, 24.318, 0.576	UBE2O, AANAT, RHBDF2, AX747521, CYGB, PRCD
cg22883290	2	127800646	8.232, 2.802,0.006	−11.023,12.589, 0.387	4.795, 11.464, 0.678	BIN1
cg02308560	19	1071176	0.895, 1.293, 0.493	1.249, 2.399, 0.606	2.389, 2.691, 0.380	CNN2, ABCA7, HMHA1, POLR2E, GPX4, SBNO2

^*Genes within 50 kb of associated CpG [4]