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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: J Cell Biochem. 2016 May 26;117(11):2482–2495. doi: 10.1002/jcb.25541

Fig. 7.

Fig. 7

c-Myc overexpression increases mRNA levels of cancer stem cell-related genes. A: qRT-PCR of CD24, DLL4, and ITGA6 mRNA after 24-hour treatment with DMSO (control) or the specified concentrations of SFN. The results shown are mean ± SD (n = 3). *Significantly different (P < 0.05) compared to corresponding DMSO-treated control or ** between PC-3/V and PC-3/Myc by one-way ANOVA with Newman-Keuls multiple comparison test. B: Immunohistochemical images for c-Myc protein expression in representative sections of prostate adenocarcinoma from a control and SFN-treated TRAMP mouse (40× objective magnification, scale bar = 50 μm). C: Quantitation of c-Myc protein staining in TRAMP tumors. The results shown are mean ± SD (n = 5). Statistical analysis was performed using Student's t-test.