. Author manuscript; available in PMC: 2017 Oct 1.

Published in final edited form as: Cerebellum. 2016 Oct;15(5):552–564. doi: 10.1007/s12311-016-0779-8

Table 3.

Comparison of mitochondrial outcomes in fibroblasts from younger and older adults with and without FXTAS

Age (y)	Mitochondrial outcomes					Reference

	Complex I	Complex II	Complex IV	Complex V	Citrate synthase
28 ± 2 (asymptomatic)	23%^*	N.D.	51%^*	64%	164%^*	This study
71 ± 2 (asymptomatic)	100%	142%	34%^*	71%	74%	[8]
68 ± 3 (FXTAS-affected)	75%	68%	56%^*	38%^*	100%	[8]

p < 0.05 vs. age- and sex-matched controls. Activities are expressed as nmol x (min x mg protein)⁻¹, normalized by citrate synthase and expressed as % of control values (age- and sex-matched), except citrate synthase. N.D. Not determined.