Table 1.
Participant characteristics, overall and by pregnancy oral antibiotic prescription, among 2128 mother-infant pairs in Project Viva
| Any antibiotic in pregnancy | |||
|---|---|---|---|
| Total (n = 2128) | Yes (n = 643) | No (n = 1485) | |
| Mean (SD) or N (%) | |||
| Maternal characteristics | |||
| Pre-pregnancy BMI, kg/m2 | 24.9 (5.6) | 25.5 (5.9) | 24.6 (5.4) |
| Age, years | 31.8 (5.2) | 31.0 (6.0) | 32.2 (4.8) |
| Nulliparous, % | |||
| No | 1111 (52.2%) | 381 (59.3%) | 730 (49.2%) |
| Yes | 1017 (47.8) | 262 (40.7) | 755 (50.8) |
| Race/ethnicity, % | |||
| Black | 348 (16.5) | 144 (22.7) | 204 (13.9) |
| Hispanic | 154 (7.3) | 69 (10.9) | 85 (5.8) |
| Asian | 120 (5.7) | 29 (4.6) | 91 (6.2) |
| White | 1399 (66.5) | 365 (57.5) | 1034 (70.4) |
| Other | 83 (3.9) | 28 (4.4) | 55 (3.7) |
| Married or cohabitating, % | |||
| No | 180 (8.6) | 81 (12.8) | 99 (6.7) |
| Yes | 1923 (91.4) | 554 (87.2) | 1369 (93.3) |
| College graduate, % | |||
| No | 744 (35.4) | 294 (46.3) | 450 (30.6) |
| Yes | 1360 (64.6) | 341 (53.7) | 1019 (69.4) |
| Household income >$70K/year, % | |||
| No | 728 (38.8) | 264 (48.7) | 464 (34.8) |
| Yes | 1146 (61.2) | 278 (51.3) | 868 (65.2) |
| Smoking status, % | |||
| Never | 1443 (68.5) | 418 (65.6) | 1025 (69.7) |
| Former | 398 (18.9) | 112 (17.6) | 286 (19.5) |
| During pregnancy | 266 (12.6) | 107 (16.8) | 159 (10.8) |
| Pregnancy weight gain, kg | 15.5 (5.7) | 15.3 (5.9) | 15.6 (5.6) |
| Mode of delivery, % | |||
| Vaginal | 1600 (76.3) | 496 (77.3) | 1104 (75.8) |
| Cesarean section | 498 (23.7) | 146 (22.7) | 352 (24.2) |
| Infant characteristics | |||
| Sex, % | |||
| Male | 1096 (51.5) | 350 (54.4) | 746 (50.2) |
| Female | 1032 (48.5) | 293 (45.6) | 739 (49.8) |
| Gestational age, wk | 39.4 (2.0) | 39.3 (1.9) | 39.5 (2.0) |
| Birth weight, g | 3461 (592) | 3429 (589) | 3475 (593) |
| BW/GA z-score | 0.17 (0.97) | 0.11 (0.98) | 0.20 (0.96) |
| Cord blood leptin, ng/ml | 9.0 (6.6) | 9.1 (6.8) | 9.0 (6.5) |
| Cord blood adiponectin, mg/ml | 28.8 (6.8) | 28.5 (6.8) | 28.9 (6.8) |
BMI, body mass index; BW-GA-z, birth weight for gestational age z-score; SD, standard deviation