TABLE 4.

H&E inflammation analysis

Group	Median	25%	75%	p < 0.05 vs. Normoxia	p < 0.05 vs. Saline
Normoxia (n = 5)	0	0	0	-	no
24-hr hyperoxia (n = 5)	0	0	0	no	no
24-hr saline (n = 4)	0.3	0.2	0.6	no	-
24-hr LPS (n = 5)	0.9	0.5	1.4	yes	no

Inflammatory changes were scored on a 0–3 scale (21): 0 = no inflammation; 1 = mild perivascular or peribronchiolar inflammatory infiltrates; 2 = moderate mixed inflammatory infiltrates throughout the lung; 3 = severe infiltration of mixed inflammatory cells. n is the number of rats. Images were scored independently by two investigators blinded to the treatment groups and compared by ANOVA on ranks.