TABLE 5.
Myeloperoxidase (MPO) analysis
| Group (n) | Median | 25% | 75% |
p < 0.05 vs. Normoxia |
p < 0.05 vs. Saline |
|---|---|---|---|---|---|
| Normoxia (n = 5) | 0 | 0 | 0 | - | no |
| 24-hr hyperoxia (n = 5) | 0 | 0 | 0 | no | no |
| 24-hr saline (n = 4) | 1.9 | 0.6 | 4.4 | no | - |
| 24-hr LPS (n = 5) | 9.6 | 3.1 | 20.0 | yes | no |
Numbers of MPO positive cells per field were counted by reviewers blinded to the treatment group and compared by ANOVA on ranks. n is the number of rats. Images from LPS-treated rats exhibited more MPO cells than normoxia rats, consistent with neutrophil infiltration.