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. 2016 Jun 2;100(4):747–760. doi: 10.1189/jlb.3A0815-359R

Figure 4. The PC61 anti-CD25 mAb enable the passive induction of EAE in Csf2−/− mice.

Figure 4.

Shown are time courses of data portrayed in Table 4. PC61-PC61, both donors and recipients were treated with PC61; PC61-Saline, donors but not recipients were treated with PC61; Saline-PC61, recipients but not donors were treated with PC61; Saline-Saline, neither donors nor recipients were treated with PC61. Shown are the means and the sem for the EAE score (A and C) and weight loss (B and D) time courses of C57BL/6 (A and B) and Csf2−/− (C and D) mice. (C) Nonparametric ANOVA; (a) vs. (c) and (d), P < 0.004 from d 8 to 40; (b) vs. (d), P < 0.001 from d 8 to 17 and P < 0.05 from d 18 to 40; and (b) vs. (a), P < 0.05 from d 17 to 29. (D) Parametric ANOVA; (a) vs. (c) and (d), P < 0.020 from d 27 to 38; (b) vs. (d), P < 0.010 from days 9 to 18; (b) vs. (c), P < 0.02 from d 9 to 20 and P < 0.05 from d 21 to 26; and (b) vs. (a), P < 0.32 from d 13 to 15.