TABLE 2.
Concentration of cBiMPS | % viable | % CD69+a | % of cells proliferatinga | % of IFN-γ-producing cellsa |
---|---|---|---|---|
No drug added | 69 ± 11 | 61 ± 21 | 48 ± 14 | 8 ± 3 |
5 mM AzA | 62 ± 13 | 66 ± 15 | 44 ± 9 | 10 ± 3 |
1 mM pentanol | 42 ± 12* | 56 ± 13 | 41 ± 15 | 9 ± 2 |
100 μM NA | 58 ± 12 | 60 ± 11 | 39 ± 13 | 7 ± 1 |
Forskolin | 8 ± 4* | 6 ± 3* | 7 ± 3* | 1 ± 1* |
No CD3/CD28 stimulation | 71 ± 14 | 1 ± 0* | 5 ± 2* | 0 ± 0* |
Groups were compared by 1-way ANOVA using Tukey’s multiple comparison test.
Only viable CD4+ cells were examined.
P < 0.05, group outcome was significantly different compared with the no-drug-added group.