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. Author manuscript; available in PMC: 2016 Sep 8.
Published in final edited form as: Cell Rep. 2016 Aug 11;16(8):2178–2186. doi: 10.1016/j.celrep.2016.07.050

Figure 1. Linc-p21 in vivo deletion overview.

Figure 1

(A) Linc-p21/Cdkn1a locus on mouse chromosome 17. Asterisks indicate known p53 binding sites. (B) Dendrogram showing the type and number of samples sequenced and the Jenson-Shanon distance, a measure of total transcriptome similarity, between their expression profiles. Wildtype shown in black, knockout shown in grey. (C) Average Linc-p21 expression profile in each tissue. Error bars represent 95% confidence interval. (D) Heatmap depicting expression of genes significantly differentially expressed in every tissue. Log2 fold-change was calculated using the average FPKMs for all replicates (KO/WT). See also Figure S1.