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. Author manuscript; available in PMC: 2016 Sep 8.
Published in final edited form as: Cell Rep. 2016 Aug 11;16(8):2178–2186. doi: 10.1016/j.celrep.2016.07.050

Figure 2. Linc-p21 transcript is not required for local gene regulation.

Figure 2

(A) Summary of local transcriptional changes upon Linc-p21 deletion (+/− 2Mb of Linc-p21). Dots represent average log2 fold change across all 6 tissues and error bars represent standard error. Red indicates significant differential expression in at least one tissue. (B-E) Expression of genes in local region (+/− 2Mb of Linc-p21) for E14.5 hindlimbs (B), heart (C), liver (D), and adult brain (E). In each plot, the Y-axis represents the log2 FPKM fold change and genes marked in red were significantly differentially expressed. The p value represents the probability that this number of genes would be differentially expressed within a region of this size. Insets show Linc-p21 and lacZ expression (FPKM) in wildtype (black) and knockout (gray). See also Figure S2.