TABLE 2.
Pig clinical signs of disease
| Treatment (no. of animals) | Gastrointestinal disease (%)a | Systemic disease (%)b | Fatal disease (%)c |
|---|---|---|---|
| Uninfected control (3) | Mild-moderate diarrhea (100), rectal prolapse (0) | 0 | 0 |
| UK6 spores + VNA2-Tcd (6) | Mild-moderate diarrhea (100), rectal prolapse (0) | 0 | 0 |
| UK6 spores + VNA2-Tcd-Adeno (9) | Mild-severe diarrhea (100), rectal prolapse (0) | 0 | 0 |
| UK6 spores + buffer (6) | Moderate-severe diarrhea (100), rectal prolapse (83) | 50 | 50 |
| UK6 spores + control-Adeno (6) | Moderate-severe diarrhea (100), rectal prolapse (50) | 33 | 50 |
a
Severity of gastrointestinal disease was determined by clinical signs of edema, hemorrhage, rectal prolapse, diarrhea, and gross and histopathologic lesions, ranging from mild to severe.
b
Systemic signs include pleural effusion and ascites.
c
Fatal disease indicates that piglets were euthanized due to the severity of the disease.