Figure 2.
Plasma leptin can predict the mortality of IPF patients independently. (a) Plasma leptin was significantly elevated in decedents (n = 33) than that in survivors (n = 23) (p = 0.007). (b) Kaplan-Meier analyses showed patients with AE-IPF had a significantly higher mortality rate compared with S-IPF subjects by log-rank test (p < 0.001). (c) Patients with plasma leptin levels above 13.79 ng/mL had a higher mortality than those with leptin levels lower than that (p = 0.003). (d) The survival had no significant difference between patients with plasma KL-6 levels >500 U/mL and those ≤500 U/mL (p = 0.286).