Table 3.
Final model of risk factors associated with 5-year decline in (A) digit span, (B) Trails-making Part B, and (C) digit symbol test performance.
| Parameter | Estimate | SE | P-value |
|---|---|---|---|
| (A) Digit span | |||
| Treatment (INT vs. STD) | −0.026 | 0.153 | 0.863 |
| African-American (yes/no) | −0.807 | 0.209 | <0.001 |
| Thiazide diuretic (yes/no) | −0.425 | 0.202 | 0.036 |
| (B) Trails B | |||
| Treatment (INT vs. STD) | 0.0024 | 0.147 | 0.987 |
| Diabetes duration (years) | −0.028 | 0.010 | 0.006 |
| Diastolic BP (mmHg) | 0.028 | 0.0091 | 0.002 |
| CCB (yes/no) | −0.639 | 0.184 | <0.001 |
| (C) Digit symbol | |||
| Treatment (INT vs. STD) | 0.067 | 0.172 | 0.697 |
| Diabetes duration (years) | −0.025 | 0.012 | 0.034 |
| CCB (yes/no) | −0.557 | 0.217 | 0.011 |
| Thiazide diuretic (yes/no) | −0.549 | 0.225 | 0.015 |
(A) N = 1159.
(B) N = 1099; BP, blood pressure; CCB-calcium channel blocker.
(C) N = 1139.