Table 2. Parameters of completed neuron models extracted from Epoch 0.
| Ion | Neuron 1 |
Neuron 2 |
||||
|---|---|---|---|---|---|---|
| Parameter | pL, pU | p* | pL, pU | p* | ||
| C | μF.cm−2 | 0.3, 4.0 | 3.80 | 0.4, 4.0 | 0.447 | |
| ENa | mV | 42, 50 | 45.57 | 40, 54 | 41.55 | |
| EK | mV | −90, −80 | −88.29 | −95, −60 | −95 | |
| ELeak | mV | −110, −40 | −64.32 | −120, −40 | −67.2 | |
| A | μm2 | 202–502 | 38.252 | 202–502 | 24.82 | |
| NaT | gNaT | mS.cm−2 | 100, 120 | 120 | 70, 130 | 70 |
| m | Vm | mV | −49, −27 | −37.85 | −52, −1 | −1.636 |
| dVm | mV | 5, 32 | 9.16 | 3, 32 | 32.0 | |
| dVtm | mV | 5, 45 | 5.0 | 3, 45 | 3 | |
| t0m | ms | 0.02, 0.7 | 0.388 | 0.001, 0.7 | 0.00647 | |
| εm | ms | 0.012, 7 | 0.012 | 0.001, 7 | 0.06239 | |
| h | Vh | mV | −79, −39 | −65.70 | −93, −9 | −29.35 |
| dVh | mV | −35, −5 | −9.76 | −35, −5 | −5 | |
| dVth | mV | 4, 43 | 41.67 | 5, 47 | 37.89 | |
| t0h | ms | 0.02, 90 | 0.02 | 0.02, 180 | 0.02 | |
| εh | ms | 1, 470 | 4.552 | 1, 970 | 13.75 | |
| NaP | gNaP | mS.cm−2 | 0, 20 | 0.0062 | 0, 19 | 0.9693 |
| m | Vm | mV | −69, −29 | −57.37 | −69, −19 | −49.80 |
| dVm | mV | 5, 32 | 9.16 | 3, 45 | 38.42 | |
| dVtm | mV | 5, 45 | 5.0 | 3, 45 | 45.0 | |
| t0m | ms | 0.02, 0.7 | 0.388 | 0.001, 7 | 1.213 | |
| εm | ms | 0.012, 7 | 0.012 | 0.001, 7 | 0.001 | |
| K1 | gK1 | mS.cm−2 | 0, 80 | 0.606 | 0, 130 | 130 |
| m | Vm | mV | −69, −21 | −21.0 | −39, 25 | 12.25 |
| dVm | mV | 5, 34 | 7.561 | 3, 34 | 4.860 | |
| dVtm | mV | 5, 34 | 20.11 | 5, 34 | 5.0 | |
| t0m | ms | 0.01, 5.4 | 0.34 | 0.01, 5.4 | 0.4557 | |
| εm | ms | 0.002, 23 | 8.556 | 0.02, 23 | 10.04 | |
| K2 | gK2 | mS.cm−2 | 0, 80 | 0.430 | 0, 80 | 1.128 |
| m | Vm | mV | −90, −21 | −42.71 | −90, −17 | −83.03 |
| dVm | mV | 5, 48 | 10.44 | 5, 48 | 48.0 | |
| dVtm | mV | 5, 48 | 7.772 | 5, 48 | 27.69 | |
| t0m | ms | 0.02, 20 | 1.889 | 0.02, 20 | 4.814 | |
| εm | ms | 0.5, 23 | 23.0 | 0.5, 143 | 94.81 | |
| h | Vh | mV | −90, −35 | −71.36 | −90, −25 | −52.68 |
| dVh | mV | −39, −5 | −7.49 | −39, −3 | −11.05 | |
| dVth | mV | −39, −5 | 38.99 | −39, −5 | −25.55 | |
| t0h | ms | 0.5, 310 | 189.7 | 0.5, 310 | 15.75 | |
| εh | ms | 0. 910 | 0.5 | 0.5, 1910 | 583.4 | |
| δh | mV | 0, 990 | 24.35 | 0, 1990 | 0 | |
| K3 | gK3 | mS.cm−2 | 0, 12 | 0 | 0, 6 | 0.5847 |
| m | Vm | mV | −25, 30 | −24.98 | −85, 10 | −25, 06 |
| dVm | mV | 10, 65 | 65 | 10, 65 | 53.92 | |
| dVtm | mV | 10, 70 | 70 | 10, 70 | 17.87 | |
| t0m | ms | 0.01, 55 | 54.97 | 0.01, 75 | 4.066 | |
| εm | ms | 0.1, 455 | 454.9 | 0.1, 1955 | 1955 | |
| CaL | gout | mS.cm−2 | 0.01, 9 | 0.119 | 0.01, 9 | 0.295 |
| ρ | 0.01, 100 | 0.514 | 0.01, 100 | 13.877 | ||
| m | Vm | mV | −56, −8 | −56.0 | −69, −8 | −14.21 |
| dVm | mV | 5, 49 | 20.49 | 5, 49 | 49.0 | |
| dVtm | mV | 5, 55 | 12.95 | 5, 55 | 21.295 | |
| t0m | ms | 0.09, 43.6 | 32.17 | 0.09, 73.6 | 22.20 | |
| εm | ms | 0.2, 295 | 295 | 0.2, 1895 | 1895 | |
| CaT | Vm | mV | −80, −35 | −78.8 | −80, −25 | −63.32 |
| m | dVm | mV | 5, 39 | 39.0 | 5, 59 | 59.0 |
| dVtm | mV | 10, 57 | 53.63 | 10, 57 | 10.0 | |
| t0m | ms | 0.02, 0.9 | 0.9 | 0.02, 0.9 | 0.02 | |
| εm | ms | 0.5, 97 | 1.596 | 0.5, 97 | 60.63 | |
| h | Vh | mV | −90, −55 | −57.04 | −85, 25 | −72.90 |
| dVh | mV | −34, −5 | −5.0 | −44, −3 | −29.64 | |
| dVt1 | mV | 3, 55 | 55.0 | 3, 95 | 43.51 | |
| dVt2 | ms | 3, 55 | 55.0 | 5, 95 | 95 | |
| t0h | ms | 5, 190 | 50.05 | 1, 190 | 11.33 | |
| εh | mV | 0.5, 7000 | 539.0 | 0.5, 1600 | 1600 | |
| HCN | gHCN | mS.cm−2 | 0, 10 | 0.013 | 0, 6 | 0.2608 |
| h | Vh | mV | −90, −40 | −75.50 | −90, −40 | −66.92 |
| dVh | mV | −30, −5 | −5.0 | −30, −3 | −8.142 | |
| dVth | mV | 5, 40 | 40.0 | 3, 50 | 4.403 | |
| t0h | ms | 0.1, 500 | 161, 8 | 0.1, 500 | 74.741 | |
| εh | mV | 0.1, 5000 | 0.1 | 0.1, 500 | 33.96 | |
| Leak | gL | mS.cm−2 | 0.01, 0.6 | 0.0794 | 0.01, 0.6 | 0.6 |