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. 2016 Sep 8;6:32682. doi: 10.1038/srep32682

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Copyright © 2016, The Author(s)

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(a) ALK-expressing NB cell expansion was repressed by co-culture with NLRR1-expressing cells. Cell expansion for 5 days was evaluated as the increase of EGFP intensity. Data are means ± s.d. (b) ALK-mutated NB cell growth was inhibited by a fixed layer of NLRR1-expressing cells. (d) exN1 abrogated ALK-mutated NB cell proliferation and the LRR domain was required for the effect. (d) pexN1 reduced SH-SY5Y cell growth. Data are means ± s.d. *P < 0.05, **P < 0.01, and ***P < 0.001.