Table 3. Distribution of RegulomeDB variants categories⁶.

Category	Description	SNPs Number
Likely to affect binding and linked to expression of a gene target
1a	eQTL + TF binding + matched TF motif + matched DNase footprint + DNase peak	1
1b	eQTL + TF binding + any motif + DNase footprint + DNase peak	5
1c	eQTL + TF binding + matched TF motif + DNase peak	0
1d	eQTL + TF binding + any motif + DNase peak	5
1e	eQTL + TF binding + matched TF motif	0
1f	eQTL + TF binding/DNase peak	25
Likely to affect binding
2a	TF binding + matched TF motif + matched DNase footprint + DNase peak	1
2b	TF binding + any motif + DNase footprint + DNase peak	24
2c	TF binding + matched TF motif + DNase peak	0
Less likely to affect binding
3a	TF binding + any motif + DNase peak	48
3b	TF binding + matched TF motif	1
Minimal binding evidence
4	TF binding + DNase peak	85
5	TF binding or DNase peak	241
6	Motif hit	226
No data#		206

eQTL = expression quantitative trait loci, TF = transcription factor, DNase = deoxyribonuclease, ^#No data is available in RegulomeDB scoring scheme.