Figure 2. Confirmation of LC-MS/MS data by western blot analysis.

(A) PLTP and MASP-1 expression in plasma samples from representative randomly selected subjects in healthy control (HC) and early and exudative AMD groups (n = 4, each) for the discovery study. (B) Plasma levels of PLTP and MASP-1 were increased in AMD patients relative to HCs in a manner that was dependent on disease severity, as determined by quantitative western blot analysis.