Table 1. Baseline characteristics of patients without acute kidney injury (AKI) at the time of intensive care unit admission.
| New AKI patients (n = 31) | Patients with no AKI (n = 102) | P value | |
|---|---|---|---|
| Age (year) | 63 (48–74) | 63 (51–73) | 0.74 |
| Male, no. (%) | 21 (68) | 59 (58) | 0.40 |
| Surgical, no. (%) | 8 (26) | 49 (48) | 0.04 |
| Sepsis, no. (%) | 14 (45) | 26 (25) | 0.04 |
| respiratory, no. (%) | 6 (43) | 15 (60) | |
| abdominal, no. (%) | 1 (7) | 2 (8) | |
| urinary, no. (%) | 1 (7) | 2 (8) | |
| others, no. (%) | 6 (43) | 6 (24) | |
| APACHE II score | 19 (15–26) | 15 (11–19) | <0.001 |
| Hypertension, no. (%) | 17 (55) | 42 (41) | 0.22 |
| Diabetes Mellitus, no. (%) | 10 (32) | 16 (16) | 0.07 |
| Baseline creatinine (mg/dL) | 0.91 (0.55–1.63) | 0.63 (0.51–0.78) | <0.001 |
| Baseline CKD, no. (%) | 10 (32) | 7 (6.9) | <0.001 |
| C-reactive protein (mg/dL) | 2.7 (0.3–9.5) | 0.9 (0.1–5.6) | 0.08 |
| White blood cell count (×103/μL) | 11.6 (5.2–16.0) | 11.8 (7.7–14.6) | 0.63 |
| Blood lactate (mmol/L) | 2.3 (1.2–4.3) | 1.6 (1.1–2.3) | 0.03 |
| Aspartate aminotransferase (IU/L) | 36 (24–57) | 29(20–38) | 0.11 |
| Alanine aminotransferase (IU/L) | 18 (13–50) | 17 (11–26) | 0.06 |
| Total bilirubin (mg/dL) | 0.7 (0.4–1.1) | 0.7 (0.5–1.1) | 0.91 |
| Serum creatinine (mg/dL) | 1.27 (0.8–2.1) | 0.65 (0.53–0.83) | <0.001 |
| Urine NGAL (ng/mL) | 123.2 (19.0–699.2) | 12.5 (4.9–34.5) | <0.001 |
| Urine L-FABP (ng/mL) | 88.1 (29.4–211.9) | 9.2 (3.5–36.0) | <0.001 |
APACHE, Acute Physiology and Chronic Health Evaluation; CKD, chronic kidney disease; NGAL, neutrophil gelatinase-associated lipocalin; L-FABP, L-type fatty acid-binding protein.