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(a) F0: no fibrosis; (b) F1: fibrous expansion of portal areas without septa (i.e., portal fibrosis); (c) F2: portal fibrosis with few septa was observed; (d) F3: fibrous expansion of portal areas with marked bridging or septa (i.e., septal fibrosis); (e) F4: the tissue is composed of nodules surrounded completely by fibrosis (i.e., cirrhosis).
