Table 1.
Demographic and clinical characteristics of episodes of incidenta allopurinol use
| All | Incident stroke during follow up | P-value | ||
|---|---|---|---|---|
| No | Yes | |||
| Total, N (episodes) | 28,488 | 26,311 | 2,177 | |
| Age | 76.5 (7.4) | 76.4 (7.4) | 78.1 (7.3) | <0.0001 |
| Gender, N (%) | <0.0001 | |||
| Male | 14,163 (49.7) | 13,185 (50.1) | 978 (44.9) | |
| Female | 14,325 (50.3) | 13,126 (49.9) | 1,199 (55.1) | |
| Race/Ethnicity, N (%) | 0.0004 | |||
| White | 22,627 (79.4) | 20,970 (79.7) | 1,657 (76.1) | |
| Black | 3,371 (11.8) | 3,049 (11.6) | 322 (14.8) | |
| Hispanic | 589 (2.1) | 538 (2.0) | 51 (2.3) | |
| Asian | 1,236 (4.3) | 1,134 (4.3) | 102 (4.7) | |
| Native American | 92 (0.3) | 83 (0.3) | 9 (0.4) | |
| Other/unknown | 573 (2.0) | 537 (2.0) | 36 (1.7) | |
| Region, N (%) | 0.013 | |||
| Northeast | 4,586 (16.6) | 4,224 (16.6) | 362 (17.3) | |
| Midwest | 6,400 (23.2) | 5,958 (23.3) | 442 (21.1) | |
| South | 11,405 (41.3) | 10,486 (41.1) | 919 (44.0) | |
| West | 5,227 (18.9) | 4,859 (19.0) | 368 (17.6) | |
| Charlson- Romano comorbidity Index Score | 3.61 (3.22) | 3.56 (3.20) | 4.27 (3.39) | <0.0001 |
aNo allopurinol use in the baseline period of 365 days