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. 2016 Jul 29;5(8):e003718. doi: 10.1161/JAHA.116.003718

Figure 7.

Figure 7

Expression of ODC and polyamine levels were downregulated in CPZ‐treated TAC‐operated mice. A, Expression of ODC mRNA in left ventricle tissue collected from vehicle control‐ and CPZ‐treated mice at 4 or 8 weeks after sham or TAC operation is shown. B, Analyses of cardiac ODC mRNA levels in the above groups (n=6 mice per group) are shown. *P<0.05, **P<0.01. C, Western blotting results from left ventricle tissue of the vehicle control‐ and CPZ‐treated mice at 4 or 8 weeks after sham or TAC operation are shown. D, Analyses of ODC protein in the above groups (n=6 mice per group) are shown. *P<0.05, **P<0.01. E, Representative figure shows the chromatographic separation of polyamines including putrescine, spermidine, and spermine in left ventricle tissue of the sham‐operated and vehicle control‐ and CPZ‐treated TAC‐operated mice. F, Measurement of polyamine level in the above group (n=6 mice per group) is shown. *P<0.05, **P<0.01 versus sham group, # P<0.05 versus TAC vehicle control group. CPZ indicates capsazepine; ODC, ornithine decarboxylase; Put, putrescine; Spd, spermidine; Spm, spermine; TAC, transverse aorta constriction.