Table 1.
General Characteristics of Normotensive Volunteers by SS‐Index Classes: Mean (SD)
| Classes | ISS (N=29) | SR (N=25) | SS (N=17) | P Value |
|---|---|---|---|---|
| SS‐Index range, mm Hg/(mol·day) | −98.2: −15.3 | −14.5: +14.3 | +15.1: +123.0 | |
| ΔMAP, mm Hga | −6.4 (3.7) | 0.0 (2.0) | 6.5 (3.9) | |
| Sex, F/M | 20/9 | 15/10 | 10/7 | 0.72 |
| Age, y | 27.3 (6.4) | 26.0 (3.8) | 29.6 (6.8) | 0.053 |
| Body mass index, kg/m2 b | 21.4 (2.6)c | 22.1 (2.4) | 23.9 (2.5) | <0.01 |
| ΔWeight, kgd | 1.4 (1.1) | 1.2 (1.6) | 0.9 (1.4) | 0.34 |
| Family history of hypertension | 21% | 36% | 41% | 0.28 |
| 24‐h systolic BP, mm Hge | 115.0 (7.7) | 116.5 (8.6) | 116.2 (11.7) | 0.82 |
| 24‐h diastolic BP, mm Hge | 68.6 (5.6) | 69.2 (6.1) | 69.8 (8.6) | 0.84 |
| 24‐h HR, bpme | 73.5 (9.0) | 70.7 (9.2) | 71.5 (10.5) | 0.53 |
BP indicates blood pressure; HR, heart rate; ISS, inverse sodium‐sensitive; SR, sodium resistant; SS, sodium sensitive.
a
ΔMAP, difference between high‐salt and low‐salt conditions in mean arterial pressure averaged over the 2‐h recording period at the end of the diet.
b
Measures at the end of the low‐sodium diet.
c
Means a significant difference vs SS (Tukey's post‐hoc).
d
ΔWeight, difference between body weights at the end of the high‐salt and low‐salt diets.
e
Data from 24‐h ambulatory BP monitoring during habitual diet; P calculated by χ2 test for sex and family history of hypertension, by 1‐way ANOVA for all the other variables.