Table 2.

Associations between anti-RgpB IgG (stratified for above the 75th percentile vs below) and the development of RA in pre-symptomatic individuals and RA patients

	Pre-symptomatic individuals (n = 251)				RA patients (n = 192)
	Simple logistic regression	Multiple logistic regression			Simple logistic regression	Multiple logistic regression
Variable	OR (95 % CI)	OR (95 % CI)			OR (95 % CI)	OR (95 % CI)
Anti-RgpB	2.31 (1.41–3.78)	2.24 (1.35–3.71)	2.55 (1.67–4.43)	2.17 (1.28–3.68)	1.20 (0.75–1.92)	1.18 (0.73–1.92)	1.30 (0.77–2.17)	1.22 (0.74–2.00)
Ever smoker		1.88 (1.26–2.78)				2.14 (1.41–3.26)
HLA-DRB1 SE			3.58 (2.36–5.42)				3.14 (2.05–4.83)
PTPN22 1858 T-variant				2.17 (1.36–3.48)				2.16 (1.33–3.53)

OR odds ratio, CI confidence interval, RA rheumatoid arthritis