Table 1.
Electrocardiographic Parameters of SCN5A‐E1784K Carriers Versus Noncarriers
| E1784K+ n=17 | E1784K− n=18 | P Value | |
|---|---|---|---|
| RR, ms | 920±258 | 865±168 | 0.46 |
| PR, ms | 196±31 | 162±17 | <0.0001 |
| QRS, ms | 100±20 | 87±13 | 0.03 |
| QTc, ms | 467±16 | 408±17 | <0.0001 |
| ST elevation V1, mV | 0.04±0.07 | 0.01±0.03 | 0.11 |
| ST elevation V2, mV | 0.04±0.07 | 0.01±0.03 | 0.08 |
| ST elevation V3, mV | 0.02±0.05 | 0.04±0.02 | 0.2 |
| Brugada type II/III | 7 | 0 | 0.008 |
| Ajmaline positive | 13/15 (87%)a | 0/11 (0%) | <0.0001 |
a
Two had to be stopped due to QRS widening >130% and the occurrence of premature ventricular contractions.