Table 2.
Mean Baseline and Change in SAQ Scores, Stratified by Treatment and eGFR
| Treatment and eGFR | SAQ Domain | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Quality of Life | Angina Frequency | Angina Stability | Physical Limitation | Treatment Satisfaction | |||||||||||
| Baseline Score, Mean (SD) | Mean (95% CI) Change in Score | P Value | Baseline Score, Mean (SD) | Mean (95% CI) Change in Score | P Value | Baseline Score, Mean (SD) | Mean (95% CI) Change in Score | P Value | Baseline Score, Mean (SD) | Mean (95% CI) Change in Score | P Value | Baseline Score, Mean (SD) | Mean (95% CI) Change in Score | P Value | |
| CABG | |||||||||||||||
| eGFR ≥90 | 51.2 (26.2) | 22.1 (18.5–25.7) | 0.38 | 78.0 (25.4) | 9.5 (6.0–12.9) | 0.39 | 64.0 (31.5) | 6.4 (1.1–11.6) | 0.32 | 64.4 (24.2) | 16.6 (13.3–19.8) | 0.57 | 88.2 (14.8) | −0.3 (−2.7 to 2.2) | 0.22 |
| eGFR 60 to 89 | 54.2 (26.4) | 23.1 (20.3–25.9) | 77.6 (25.0) | 11.1 (8.4–13.8) | 62.4 (30.7) | 8.5 (4.3–12.6) | 63.1 (23.2) | 17.2 (14.7–19.8) | 87.7 (16.2) | 1.6 (−0.3 to 3.6) | |||||
| eGFR 45 to 59 | 55.1 (27.1) | 24.6 (20.8–28.4) | 76.9 (25.9) | 12.5 (8.9–16.2) | 60.5 (27.7) | 8 (2.4–13.6) | 60.5 (23.8) | 15.6 (12.1–19.0) | 87.4 (15.1) | 1.7 (−1.0 to 4.3) | |||||
| eGFR 30 to 44 | 56.2 (24.8) | 22.6 (16.8–28.4) | 77.9 (26.9) | 13.3 (7.8–18.8) | 61.0 (29.2) | 13.2 (4.7–21.7) | 54.7 (25.2) | 18.5 (13.2–23.7) | 86 (16.1) | 4.3 (0.3–8.3) | |||||
| eGFR <30 | 58.2 (28.1) | 14.0 (2.3–25.6) | 79.1 (26.9) | 5.9 (−5.2 to 17.1) | 50 (34.4) | 20.8 (3.8–27.9) | 41.7 (17.4) | 19.3 (8.8–29.9) | 84.2 (18.6) | 1.8 (−6.2 to 9.9) | |||||
| Overall | 53.9 (26.5) | 22.8 (20.2–25.4) | 77.6 (25.37) | 11.3 (8.8–13.8) | 62.3 (30.4) | 8.4 (4.5–12.2) | 62.3 (23.8) | 17.4 (15.0–19.8) | 87.0 (15.8) | 1.5 (−0.3 to 3.3) | |||||
| PCI | |||||||||||||||
| eGFR ≥90 | 64.4 (24.3) | 5.8 (2.9–8.7) | 0.51 | 82.0 (22.2) | 3.6 (0.8–6.4) | 0.86 | 76.8 (29.5) | −6.2 (−10.4, −1.9) | 0.31 | 76.5 (22.0) | 5.7 (3.1–8.3) | 0.61 | 87.5 (15.5) | −1.6 (−3.6 to 0.5) | 0.83 |
| eGFR 60 to 89 | 67.3 (23.1) | 7.0 (4.3–9.6) | 84.2 (21.5) | 3.2 (0.7–5.8) | 78.7 (27.2) | −7.7 (−11.6, −3.8) | 75.7 (23.1) | 6.1 (3.7–8.5) | 89.0 (14.7) | −1.8 (−3.7 to 0.0) | |||||
| eGFR 45 to 59 | 68.6 (23.2) | 7.2 (4.1–10.3) | 83.9 (23.0) | 2.9 (−0.1 to 5.9) | 75 (28.1) | −6.0 (−10.6, −1.5) | 71.9 (24.1) | 5.5 (2.7–8.3) | 89.5 (14.1) | −1.8 (−4.0 to 0.3) | |||||
| eGFR 30 to 44 | 68.8 (23.2) | 5.8 (1.5–10.2) | 82.8 (24.0) | 3.8 (−0.3 to 8.0) | 79.0 (27.5) | −10.7 (−17.0, −4.3) | 63.3 (24.7) | 6.8 (2.8–10.7) | 88.7 (14.2) | −2.7 (−5.7 to 0.3) | |||||
| eGFR <30 | 63.7 (26.4) | 10.0 (1.4–18.7) | 87.2 (19.9) | 0.4 (−7.9 to 8.7) | 77.3 (26.1) | −1.5 (−14.2, 11.2) | 56.8 (25.0) | 9.8 (2.0–17.7) | 91.2 (13.4) | −1.8 (−7.8 to 4.2) | |||||
| Overall | 66.8 (23.5) | 6.6 (4.0–9.1) | 83.6 (22.0) | 3.4 (1.0–5.8) | 77.8 (27.9) | −7.3 (−11.0 to −3.6) | 74.9 (23.3) | 6.4 (4.1–8.7) | 88.7 (14.8) | −1.6 (−3.7 to 0.1) | |||||
| Medicine | |||||||||||||||
| eGFR ≥90 | 60.5 (24.1) | 5.4 (2.0–8.8) | 0.28 | 79.6 (22.7) | 1.9 (−1.4 to 5.1) | 0.43 | 64.9 (27.0) | 0.2 (−4.8 to 5.2) | 0.59 | 72.4 (23.8) | 2.7 (−0.4 to 5.8) | 0.5 | 83.4 (18.1) | −1.8 (−4.2 to 0.5) | 0.58 |
| eGFR 60 to 89 | 66.2 (23.4) | 5.5 (2.8–8.3) | 83.1 (21.4) | 1.1 (−1.6 to 3.7) | 66.5 (26.8) | −1.4 (−5.4 to 2.7) | 71.7 (23.8) | 2.9 (0.4–5.4) | 85 (16.9) | −1.1 (−3.0 to 0.8) | |||||
| eGFR 45 to 59 | 67.9 (23.1) | 2.8 (−0.7 to 6.3) | 83.9 (20.9) | −1.2 (−4.6 to 2.1) | 63.9 (25.9) | −1.4 (−6.5 to 3.8) | 66.9 (24.6) | 2.4 (−0.8 to 5.6) | 86.3 (15.3) | −2.6 (−5.0, −0.1) | |||||
| eGFR 30 to 44 | 65.7 (23.3) | 4.4 (−0.3 to 9.1) | 79.5 (23.4) | 1 (−3.4 to 5.5) | 60.9 (28.67) | −1.9 (−8.8 to 4.9) | 62.4 (22.5) | 2.8 (−1.4 to 7.1) | 85.8 (14.7) | −1.8 (−5.0, 1.5) | |||||
| eGFR <30 | 62.0 (23.8) | 8.9 (1.4–16.3) | 82.7 (24.0) | −0.1 (−7.2 to 7.0) | 70.0 (25.3) | −7.9 (−18.8 to 2.9) | 54.0 (27..0) | 7.5 (0.8–14.2) | 85.0 (16.3) | −0.3 (−5.4 to 4.8) | |||||
| Overall | 65.3 (23.6) | 4.9 (2.4–7.5) | 82.3 (21.9) | 0.9 (−1.5 to 3.4) | 65.5 (26.8) | −1.3 (−5.0 to 2.5) | 70.0 (24.2) | 3.5 (1.2–5.8) | 85.0 (16.8) | −1.3 (−3.0 to 0.5) | |||||
eGFR indicates estimated glomerular filtration rate (mL/min per 1.73m2); SAQ, Seattle Angina Questionnaire.