Figure 2.
LIGHT (an acronym for homologous to lymphotoxins, exhibits inducible expression, and competes with herpes simplex virus glycoprotein D for herpes virus entry mediator, a receptor expressed by T lymphocytes, also known as TNFSF14)‐induced TG2 mRNA in kidneys. Wild‐type mice were infused with recombinant mouse LIGHT for either 5 or 14 days. Kidneys were obtained, and RNA was extracted and analyzed by quantitative RT‐PCR for TG2 mRNA. Data are expressed as mean±SEM; *P<0.05 vs saline‐infused mice; # P<0.05 vs hypoxia inducible factor (HIF)‐1αf/f+LIGHT‐infused mice. n=6 for all groups except for WT+saline day 14, WT+LIGHT day 14, where n=8.