Table 3.
Studies Comparing PET or PET-CT With CT Alone for Staging of Lymphomas
| Study | Year | PET or PET-CT | No. of Patients | Disease | Upstaging (%) | Downstaging (%) | Management Change (%) |
|---|---|---|---|---|---|---|---|
| Bangerter et al106 | 1998 | PET | 44 | HL | 12 | 2 | 14 |
| Partridge et al107 | 2000 | PET | 44 | HL | 41 | 7 | 25 |
| Jerusalem et al108 | 2001 | PET | 33 | HL | 10 | 10 | 3 |
| Weihrauch et al109 | 2002 | PET | 22 | HL | 18 | 0 | 5 |
| Munker et al110 | 2004 | PET | 73 | HL | 29 | 3 | NS |
| Naumann et al111 | 2004 | PET | 88 | HL | 13 | 8 | 20 |
| Hutchings et al9 | 2006 | Mostly PET-CT | 99 | HL | 19 | 5 | 9 |
| Rigacci et al10 | 2007 | Mostly PET | 186 | HL | 14 | 1 | 6 |
| Buchmann et al112 | 2001 | PET | 52 | HL (n = 27), NHL (n = 25) | 8 | 0 | 8 |
| Wirth et al113 | 2002 | PET | 50 | HL (n = 19), NHL (n = 31) | 14 | 0 | 18 |
| Raanani et al11 | 2006 | PET-CT | 103 | HL (n = 32), NHL (n = 68) | 31 | 1 | 25 |
| Elstrom et al12 | 2008 | PET-CT | 61 | HL and NHL | 18 | 0 | 5 |
| Pelosi et al13 | 2008 | PET | 65 | HL (n = 30), NHL (n = 35) | 11 | 5* | 8 |
| Karam et al14 | 2006 | PET | 17 | FL | 41 | 0 | 29 |
| Janikova et al15 | 2008 | Mostly PET | 82 | FL | NS | NS | 18 |
| Wirth et al16 | 2008 | PET | 42 | FL stages I-II on CT | 29 | 0 | 45 |
| Le Dortz et al17 | 2010 | PET-CT | 45 | FL | 8 | 0 | 18 |
| Luminari et al18 | 2013 | PET-CT | 142 | FL | 11 | 1 | NS |
Abbreviations: CT, computed tomography; FL, follicular lymphoma; HL, Hodgkin lymphoma; NHL, non-Hodgkin lymphoma; NS, not stated; PET, positron emission tomography.
*
False negative.