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. 2015 Jul 13;33(23):2563–2577. doi: 10.1200/JCO.2015.61.6706

Table 2.

Bevacizumab, Carboplatin, and Paclitaxel Versus Carboplatin Versus Carboplatin Plus Paclitaxel (control; Fig 3)

Measure Score/Result
Clinical benefit score (maximum, 180 points)
    Improvement ([12.3 − 10.3]/10.3 = 19%)
    OS score (1 × 16) 16
Toxicity score (maximum, 20 points)
    Carboplatin plus paclitaxel (control) 15 (grade 3 to 5)
    Bevacizumab, carboplatin, and paclitaxel 22 (grade 3 to 5)
    Toxicity score ([22 − 15]/15 = 46%) 0
Bonus points (maximum, 30 points)
    Palliation 0
    Treatment-free interval 0
    Total bonus points 0
Net health benefit (maximum, 130 points) 16
Drug cost (monthly)
    Drug acquisition cost $11,907.87
    Patient copay Calculated per patient

Abbreviation: OS, overall survival.