Table 5. Crude and adjusted ORs according to sociodemographic characteristics, for the risk of suffering frequent exacerbations in the following year.
| IE | FE | ORc | 95% CI | ORa | 95% CI | |
|---|---|---|---|---|---|---|
| N=568 | N=332 | |||||
| Age—per 10-year increase | — | — | 1.35 | 1.19–1.53 | 1.27 | 1.07–1.5 |
|
Gender | ||||||
| Female | 123 | 71 | 1 | — | 1 | — |
| Male | 445 | 261 | 1.02 | 0.73–1.41 | 1.07 | 0.68–1.68 |
|
Smoking | ||||||
| Never-smoker | 84 | 51 | 1 | — | 1 | — |
| Former smokers | 289 | 210 | 1.2 | 0.81–1.77 | 1.11 | 0.66–1.89 |
| Current smokers | 166 | 62 | 0.62 | 0.39–0.97 | 0.76 | 0.42–1.39 |
| Linear P trend | 0.009 | 0.228 | ||||
|
BMI | ||||||
| Normal weight (18.5–24.9) | 91 | 61 | 1 | — | 1 | — |
| Overweight (25–29.9) | 198 | 112 | 0.84 | 0.57–1.26 | 0.85 | 0.51–1.41 |
| Obesity (⩾30) | 213 | 123 | 0.86 | 0.58–1.28 | 0.82 | 0.5–1.34 |
| Underweight (<18.5) | 4 | 6 | 2.24 | 0.61–8.26 | 0.83 | 0.19–3.58 |
| Linear P trend | 0.831 | 0.463 | ||||
|
BODE-BMIa | ||||||
| BMI >21 | 484 | 285 | 1 | — | 1 | — |
| BMI ⩽21 | 22 | 17 | 1.31 | 0.68–2.51 | 1.47 | 0.66–3.26 |
Abbreviations: BMI, body mass index; CI, confidence interval; COPD, chronic obsrtuctive pilmonary disease; FE, frequent exacerbations in the following year; IE, infrequent exacerbations in the following year; OR, odds ratio; ORa, adjusted OR by age, gender, smoking status, COPD severity (GOLD grades 1–4) and FE phenotype (yes/no) in the previous year; ORc, crude OR.
a
Risk cutoff point for BMI according to BODE index.