. 2016 Sep 1;14(7):395–406. doi: 10.1089/adt.2016.730

Table 1.

Panel of Breast Cancer Cell Lines

		Mutation Status
Cell Line	Subclass	PTEN^a	PI3K^b
MCF7	ER^c	WT^d	E545K
T47D	ER	WT	H1047R
MDA-MB-231	TN^e	WT	WT
MDA-MB-157	TN	WT	WT
HCC1569	HER2^f	WT	WT
SKBR3	HER2	WT	WT
HCC1954	HER2	?^g	H1047R
KPL4	HER2	?	H1047R

^{^a}

Phosphatase and tensin homolog.

^{^b}

Phosphoinsitide-3-kinase.

^{^c}

Estrogen receptor.

^{^d}

Wild type.

^{^e}

Triple negative.

^{^f}

Human epidermal growth factor receptor 2.

^{^g}

Lack of consensus regarding the mutational status of those cell lines.

ER, estrogen receptor; HER2, human epidermal growth factor; PI3K, phosphoinositide 3-kinase; PTEN, phosphatase and tensin homolog; TN, triple negative; WT, wild type.