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Effect of mutations on RPE65 isomerase activity
| Mutant | Mean Activity |
SD | n |
|---|---|---|---|
| P25L | 7.75 | 1.4 | 10 |
| L22P | 13.5 | 1.6 | 6 |
| Y79H | 2.5 | 0.6 | 7 |
| E95Q | 6.1 | 1.1 | 6 |
Activity is represented as % of wildtype RPE65 isomerase activity; with the SDS and number of replicates.
