Figure 5. Representative images of histological sections focused on a thread.
The conditions are the same as for Figure 4. Dense woven bone entirely filled the thread of bare TA6V implants without fibrosis interposition between bone and implant as soon as 4 weeks post-implantation. Bone tissue also filled the thread of PEEK implants over time. In contrast, bone tissue within threads of BMP-2 film-coated implants appeared immature and displayed a high bone-forming activity as shown by the presence of numerous embedded osteocytes and osteoblasts laying down osteoid tissue. (scale bare 100 µm). (B) bone tissue; (v) blood vessel; (BM) bone marrow tissue; (white arrowhead) osteoid osteoblasts; (red arrows) lining osteoblasts. (scale bare 100 µm).