Table 3.
Changes in cyst characteristics from baseline to 12 months
| Variable | Placebo (n = 14) | Sirolimus (n = 17) | P Value | |
|---|---|---|---|---|
| Inspiratory | Change in median inspiratory cyst volume percentage | +0.44% (+0.01%, +2.45%) | +1.97% (−0.12%, +2.96%) | 0.60 |
| Change in total cyst number | −495 (−853, −180) | −180 (−1,118, +412) | 0.46 | |
| Change in median cyst volume, ml | +2.88 (+0.46, +5.02) | +1.72 (+0.52, +5.98) | 0.74 | |
| Expiratory | Change in median expiratory cyst volume percentage | +2.68% (+0.62, +4.18) | +0.97% (−0.28, +2.32) | 0.10 |
| Change in total cyst number | +676 (−229, +1,704) | +356 (−257, +813) | 0.42 | |
| Change in median cyst volume, ml | +1.79 (+0.53, +3.36) | +0.42 (−0.32, +3.04) | 0.15 | |
Upper and lower quartiles are given in parentheses.