Table 4.
Changes in computed tomography–derived lung volumes from baseline to 12 months
| Variable | Placebo (n = 14) | Sirolimus (n = 17) | P Value |
|---|---|---|---|
| Change in median TLC, ml | +19.0 (−67.2, +129.7) | +25.5 (−158.8, +165.6) | 0.77 |
| Change in median VC, ml | −190.4 (−584.9, −65.6) | +15.5 (−221.4, +305.8) | 0.075 |
| Change in median RV, ml | +214.4 (+109.2, +432.6) | +2.92 (−263.9, +246.9) | 0.054 |
| Change in RV/TLC | +0.05 (0.02, 0.08) | −0.01 (−0.05, 0.05) | 0.0498 |
Definition of abbreviations: RV = residual volume; TLC = total lung capacity.
Upper and lower quartiles are given in parentheses.